all-trans-Retinoic Acid

• Catalog No.: R250200
• CAS Number: 302-79-4
• M. F.: C20H28O2
• M. W.: 300.43512
• Storage: Amber Vial, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• IUPAC Traditional name: tretinoin
• Synonyms: tretinoin; ATRA; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid; Retinova; Aberel; Avita; Vitamin A acid; Retin-A

DATABASE IDS

• CAS Number: 302-79-4

PROPERTIES

• Apperance: Yellow-Orange Solid
• Melting Point: 168-170°C
• Solubility: Dimethyl Sulfoxide (25mg/ml)
• Solubility: Ethanol (25 mg/ml)
• Storage Condition: Amber Vial, -20°C Freezer, Under Inert Atmosphere
• Storage Warning: Store Dry in Freezer at -20°C for up to 1 year; in Solution

DETAILS

Description (English)

Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR); mediates cellular growth and differentiation.

REFERENCES

• Kamm, J.J., et al.: J. Am. Acad. Dermatol., 6, 652 (1982)
• Warrel, R.P., et al.: Leukemia, 8, 929 (1982)
• Sasai, Y., et al.: J. Neurol., 249, 41 (1982)