13-cis-RETINOIC ACID

• Catalog No.: R250000
• CAS Number: 4759-48-2
• M. F.: C20H28O2
• M. W.: 300.43512
• Storage: -86°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• IUPAC Traditional name: isotretinoin
• Synonyms: Ro 4-3780; Isotretinoin; Roaccutane; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2Z,4E,6E,8E-nonatetranenoic Acid; 13-cis-Vitamin A Acid; Isotrex; IsotrexGel; Neovitamin A Acid; Roaccutan; Accutane

DATABASE IDS

• CAS Number: 4759-48-2

PROPERTIES

• Apperance: Yellow-Orange Solid
• Melting Point: 176-178°C
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Ethanol (slightly)
• Solubility: Ether
• Solubility: Ethyl Acetate
• Solubility: Isopropanol
• Storage Condition: -86°C Freezer, Under Inert Atmosphere
• Storage Warning: Moisture, Temperature, Light Sensitive, Store in freezer

DETAILS

Description (English)

Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.

REFERENCES

• Lerche, C., et al.: Exp. Dermatol., 17, 972 (2008)
• Sato, T., et al.: J. Med. Chem., 51, 7705 (2008)
• Gan, J., et al.: Chem. Res. Toxicol., 22, 690 (2008)
• Macejova, D., et al.: Toxicol. Lett., 184, 114 (2008)
• Chen, P., et al.: Toxicol. App. Pharmacol.,