9-cis-Retinoic Acid

• Catalog No.: R245000
• CAS Number: 5300-03-8
• M. F.: C20H28O2
• M. W.: 300.43512
• Storage: Amber Vial, -86°C Freezer

SYNONYMS

• IUPAC name: (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• IUPAC Traditional name: alitretinoin
• Synonyms: NSC 659772; Panretyn; LGD 100057; AGN 192013; Panretin; alitretinoin; (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic Acid; ALRT 1057; LG 100057; LGD 1057; Panrexin; 9-cis-Tretinoin

DATABASE IDS

• CAS Number: 5300-03-8

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 189-191°C
• Solubility: Dimethyl Sulfoxide (25mg/ml)
• Solubility: Ethanol (25 mg/ml)
• Storage Condition: Amber Vial, -86°C Freezer
• Storage Warning: Store Dry in Freezer at -20°C for up to 1 year; in Solution

DETAILS

Description (English)

An endogenous retinoic acid isomer, which is capable of binding to both retinoic acid receptors (RAR) and retinoid X receptors (RXR). A biologically active ligand for members of the RAR and RXR subfamilies, implying that it may play a critical role in r

REFERENCES

• Allenby, G., et al.: Proc. Natl. Acad. Sci. U.S.A., 90, 30 (1993)
• Heyman, R.A., et al.: Cell, 68, 397 (1992)
• Levin, A.A., et al.: Nature, 355, 359 (1992)