Retigabine N-β-D-Glucuronide

• Catalog No.: R189060
• CAS Number: 191873-41-3
• M. F.: C22H26FN3O8
• M. W.: 479.4555432

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6R)-6-({2-[(ethoxycarbonyl)amino]-5-{[(4-fluorophenyl)methyl]amino}phenyl}amino)-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6R)-6-({2-[(ethoxycarbonyl)amino]-5-{[(4-fluorophenyl)methyl]amino}phenyl}amino)-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 1-Deoxy-1-[[2-[(ethoxycarbonyl)amino]-5-[[(4-fluorophenyl)methyl]amino]phenyl]amino] β-D-Glucopyranuronic Acid

DATABASE IDS

• CAS Number: 191873-41-3

DETAILS

Description (English)

Retigabine N-β-D-Glucuronide is the major metabolite of the antiepileptic drug Retigabine (R189050) that is produced via N-glucuronidation in humans.

REFERENCES

• Hiller, A. et al.: Drug Metab. Dispos., 27, 605 (1999)
• Borlak, J. et al.: Metab. Clin. Exp., 55, 711 (1999)
• McNeilly, P.P. et al.: Zenobiotica, 27, 431 (1999)