Ramosetron Hydrochloride

• Catalog No.: R113050
• CAS Number: 132907-72-3
• M. F.: C17H18ClN3O
• M. W.: 315.79732
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (6R)-6-(1-methyl-1H-indole-3-carbonyl)-4,5,6,7-tetrahydro-1H-1,3-benzodiazole hydrochloride
• IUPAC Traditional name: (5R)-5-(1-methylindole-3-carbonyl)-4,5,6,7-tetrahydro-3H-1,3-benzodiazole hydrochloride
• Synonyms: Irribow; (R)-(-)-Ramosetron Hydrochloride; (-)-(R)-5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H- benzimidazole Monohydrochloride; (1-Methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]methanone Hydrochloride; YM 060

DATABASE IDS

• CAS Number: 132907-72-3

PROPERTIES

• Apperance: White Solid
• Melting Point: 244-246°C
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Selective serotonin 5HT3, receptor antagonist; structurally different from Ondansetron (O655000), Granisetron (G780000). Antiemetic.

REFERENCES

• Miyata, K., et al.: J. Pharmacol. Exp. Ther., 259, 15 (1991)
• Miura, H., et al.: Biomed. Chromatogr., 8, 103 (1991)
• Tabata, H., et al.: Arzneim.-Forsch., 45, 760 (1991)