Raltegravir β-D-Glucuronide

• Catalog No.: R100310
• CAS Number: 952654-62-5
• M. F.: C26H29FN6O11
• M. W.: 620.5404632
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-[(4-{[(4-fluorophenyl)methyl]carbamoyl}-1-methyl-2-{2-[(5-methyl-1,3,4-oxadiazol-2-yl)formamido]propan-2-yl}-6-oxo-1,6-dihydropyrimidin-5-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-[(4-{[(4-fluorophenyl)methyl]carbamoyl}-1-methyl-2-{2-[(5-methyl-1,3,4-oxadiazol-2-yl)formamido]propan-2-yl}-6-oxopyrimidin-5-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 952654-62-5

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 150-152°C
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Raltegravir.

REFERENCES

• Bosma, P., et al.: J. Biol. Chem., 269, 17960 (1994)
• Richman, D., et al.: Nature, 410, 995 (1994)
• Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (1994)
• Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (1994)