Raloxifene 4'-Glucuronide

• Catalog No.: R100020
• CAS Number: 182507-22-8
• M. F.: C34H35NO10S
• M. W.: 649.7074
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-[4-(6-hydroxy-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-2-yl)phenoxy]oxane-2-carboxylic acid
• IUPAC Traditional name: (2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-[4-(6-hydroxy-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-2-yl)phenoxy]oxane-2-carboxylic acid
• Synonyms: 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-β-D-glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 182507-22-8

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 209-213°C (dec.)
• Solubility: DMF
• Solubility: DMSO
• Solubility: Hot Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Raloxifene, a nonsteroidal estrogen receptor mixed agonist/antagonist.

REFERENCES

• Dodge, J., et al.: Bioorg. Med. Chem. Lett., 7, 993 (1997)
• Jeong, E., et al.: Drug Metab. Dispos., 33, 785 (1997)
• Trontelj, J., et al.: Pharmacol. Res., 52, 334 (1997)
• Oswald, S., et al.: Clin. Pharmacol. Ther., 79 206 (1997)