(+)-Quisqualic Acid

• Catalog No.: Q825000
• CAS Number: 52809-07-1
• M. F.: C5H7N3O5
• M. W.: 189.12618
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2R)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid
• IUPAC Traditional name: (2R)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid
• Synonyms: L-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic Acid; (αS)-α-Amino-3,5-dioxo-1,2,4-Oxadiazolidine-2-propanoic Acid; L-Quisqualic Acid

DATABASE IDS

• CAS Number: 52809-07-1

PROPERTIES

• Apperance: Off-White to Pale Brown Solid
• Melting Point: 185-187°C dec.
• Solubility: Water
• Storage Condition: Refrigerator
• Storage Warning: Store in freezer at -20°C

DETAILS

Description (English)

An amino acid that is able to function as an agonist at multiple excitatory amino acid receptor substrates in the central nervous system. It also has high affinity for the kainate, AMPA and the metabotropic receptors. Inhibits the Ca2+/Cl-dependent glu

REFERENCES

• Honore, T., et al.: J. Neurochem., 38, 173 (1982)
• Schoepp, D., et al.: J. Neurochem., 50, 1605 (1982)
• Recasens, M., et al.: Neurochem. Int., 13, 463 (1982)
• Subasinghe, N., et al.: J. Med. Chem., 35, 4602 (1992)