Queuine Dihydrochloride

• Catalog No.: Q525000
• CAS Number: 86496-18-6
• M. F.: C12H15N5O3
• M. W.: 277.2792

SYNONYMS

• IUPAC name: 2-amino-5-({[(4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one
• IUPAC Traditional name: 2-amino-5-({[(4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-1H,7H-pyrrolo[2,3-d]pyrimidin-4-one
• Synonyms: 2-Amino-5-[[[(1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl]amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Dihydrochloride; [1S-(1α,4β,5β)]-2-Amino-5-[[(4,5-dihydroxy-2-cyclopenten-1-yl)amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Dihydrochloride

DATABASE IDS

• CAS Number: 86496-18-6

DETAILS

Description (English)

It is one of the modified base which is found at first anticodon position of specific tRNAs. Queuine promotes cell death and participates in regulation of cell proliferation.

REFERENCES

• Katze, J., et al.: Biochemistry, 23, 1171 (1984)
• Reisser, T., et al.: Eur. J. Biochem., 221, 979 (1984)
• Jin, Z., et al.: J. Biol. Chem., 281, 14446 (1984)