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β-Pseudouridine

Catalog No. P839605 Name Toronto Research Chemicals
CAS Number 1445-07-4 Website http://www.trc-canada.com
M. F. C9H12N2O6 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
5-[(2S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC Traditional name
5-[(2S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dihydropyrimidine-2,4-dione
Synonyms
Pseudouridine
ψ-Uridine
Pseudouridine C
β-D-Pseudouridine
5-β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione
5-(β-D-Ribofuranosyl)uracil
5-Ribosyluracil
NSC 162405

DATABASE IDS

CAS Number 1445-07-4

PROPERTIES

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DETAILS

Description (English)
An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called Ψ synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Stu

REFERENCES

  • Ferré-D'Amaré A.R. et al.: Curr. Opin. Struct. Biol., 13, 49 (2003)
  • Hamma, T. et al.: Chem. Biol., 13, 1125 (2003)
  • Liang, X.H. et al.: RNA, 8, 237 (2003)
  • Monobe, M. et al.: Mut. Res. Gen. Toxicol. Env. Mutagen., 538, 93 (2003)