Prostratin

• Catalog No.: P838800
• CAS Number: 60857-08-1
• M. F.: C22H30O6
• M. W.: 390.47

SYNONYMS

• IUPAC name: (1R,2S,6R,10S,11R,13S,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-13-yl acetate
• IUPAC Traditional name: prostratin
• Synonyms: 12-Deoxyphorbol 13-acetate; (1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one; Stillingia Factor S7; NSC 623310; 13-O-Acetylphorbol

DATABASE IDS

• CAS Number: 60857-08-1

DETAILS

Description (English)

It is a protein kinase C activator found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). Research indicated that prostratin has potential to be useful in the treatment of HIV as it flushes viral reservoirs in latently infecte

REFERENCES

• Reuben, et al.: Clin. Cancer Res., 6, 1671 (2000)
• Korin, Y., et al.: J. Virol., 76, 8118 (2000)
• Wei, X., et al.: Nature, 422, 307 (2000)
• Kutsch, O., et al.: Antimicrob. Agents Chemother., 48, 1652 (2000)