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Pregnenolone

Catalog No. P712200 Name Toronto Research Chemicals
CAS Number 145-13-1 Website http://www.trc-canada.com
M. F. C21H32O2 Telephone +1 (416) 665-9696
M. W. 316.47758 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 2503

SYNONYMS

IUPAC name
1-[(1S,2R,5S,10S,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-7-en-14-yl]ethan-1-one
IUPAC Traditional name
pregnenolone
Synonyms
Skinostelon
5-Pregnenolone
(3β)-3-Hydroxy-pregn-5-en-20-one
Bina-Skin
(3β)-3-Hydroxypregn-5-en-20-one
Arthenolone
Enelone
NSC 1616
Pregnolon
Prenolon
Regnosone

DATABASE IDS

CAS Number 145-13-1

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 174-177°C
Solubility Chlorform
Solubility Ethanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus.

REFERENCES

  • Geick, A., et al.: J. Biol. Chem., 276, 14581 (1976)
  • Johnson, D., et al.: Toxicol. Sci., 66, 16 (1976)
  • Abe, C., et al.: Lipids, 42, 637 (1976)
  • Bjondahl, K., et al.: Med. Biol., 54, 454 (1976)