Pravastatin Lactone

• Catalog No.: P701190
• CAS Number: 85956-22-5
• M. F.: C23H34O6
• M. W.: 406.51246
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S,3S,7S,8S,8aR)-3-hydroxy-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
• IUPAC Traditional name: (1S,3S,7S,8S,8aR)-3-hydroxy-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
• Synonyms: R 414; (2S)-2-Methylbutanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester

DATABASE IDS

• CAS Number: 85956-22-5

PROPERTIES

• Apperance: White Crystalline PowderOff-White Solid
• Melting Point: 140-143°C
• Solubility: Chloroform
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Pravastatin Lactone is a metabolite of Pravastatin (P702000).

REFERENCES

• Boberg, M., et al.: Drug Metab. Dispos., 25, 321 (1997)
• Neuvonen, P., et al.: Clin. Pharmacol. Ther., 63, 332 (1997)
• Boyd, R., et al.: J. Clin. Pharmacol., 40, 91 (1997)