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Polythiazide

Catalog No. P689410 Name Toronto Research Chemicals
CAS Number 346-18-9 Website http://www.trc-canada.com
M. F. C11H13ClF3N3O4S3 Telephone +1 (416) 665-9696
M. W. 439.8818296 Fax +1 (416) 665-4439
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Storage Chembase ID: 1158

SYNONYMS

IUPAC name
6-chloro-2-methyl-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
IUPAC Traditional name
polythiazide
Synonyms
6-Chloro-3,4-dihydro-2-methyl-3-[[2,2,2-trifluoroethyl)thio]methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide
Nephril
Drenusil
Renese
(±)-Polythiazide
(±)-Nephril
6-Chloro-3,4-dihydro-2-methyl-7-sulfamoyl-3-(2,2,2-trifluoroethylthiomethyl)-2H-1,2,4-benzothiadiazine 1,1-Dioxide
NSC 108161
P 2525

DATABASE IDS

CAS Number 346-18-9

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Polythiazide is a thiazide diuretic. Polythiazide is used in the treatment of hypertension as well as nephrotic syndrome, cirrhosis of the liver, and nutritional edema.

REFERENCES

  • Kaur, J. et al.: J. Ind. Med. Assoc., 48, 13, (1967)
  • Lund-Johansen, P.: Acta Med. Scand., 187, 509 (1967)
  • O'Brien, E.T. et al.: Br. Heart J., 34, 1042 (1967)