Polymyxin B Sulfate

• Catalog No.: P689400
• CAS Number: 1405-20-5
• M. F.: C56H98N16O13
• M. W.: 1203.47672
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (6S)-N-(3-amino-1-{[(2R)-1-[(3-amino-1-{[(18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl)carbamoyl]-2-hydroxypropyl]carbamoyl}propyl)-6-methyloctanamide
• IUPAC Traditional name: (6S)-N-(3-amino-1-{[(2R)-1-[(3-amino-1-{[(18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl)carbamoyl]-2-hydroxypropyl]carbamoyl}propyl)-6-methyloctanamide
• Synonyms: N-[3-Amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-6-methyl-octanamide Sulfuric Acid

DATABASE IDS

• CAS Number: 1405-20-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 217-220°C (dec.)
• Solubility: Water
• Storage Condition: Refrigerator

DETAILS

Description (English)

Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixture of Polymyxin B1 and B2 sulfate.Biological potency (d

REFERENCES

• Coppi, G., et al.: J. Pharm. Pharmacol., 60, 21 (2008)
• Roche, S., et al.: Food Microbiol., 26, 21 (2008)
• Kawanishi, T., et al.: Plant Pathol., 58, 237 (2008)