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Plevitrexed

Catalog No. P625000 Name Toronto Research Chemicals
CAS Number 153537-73-6 Website http://www.trc-canada.com
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Storage Chembase ID: 176828

SYNONYMS

IUPAC name
(2S)-2-[(4-{[(2,7-dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}-2-fluorophenyl)formamido]-4-(1H-1,2,3,4-tetrazol-5-yl)butanoic acid
IUPAC Traditional name
plevitrexedumplevitrexed
Synonyms
BGC 9331
(αS)-α-[[4-[[(1,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-1H-tetrazole-5-butanoic Acid
ZD 9331
NSC 696259
Vamidex

DATABASE IDS

CAS Number 153537-73-6

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
A novel non-polyglutamated thymidylate synthase inhibitor, in adult patients with solid tumors.

REFERENCES

  • Sirotnak, F., et al.: Cancer Res., 45, 3992 (1985)
  • Touroutoglou, N., et al.: Clin. Cancer Res., 2, 227 (1985)
  • Twelves, C., et al.: Clin. Cancer Res., 5, 1696 (1985)
  • Goh, B., et al.: J. Clin. Oncol., 19, 1476 (1985)