Piperlongumine

• Catalog No.: P482850
• CAS Number: 20069-09-4
• M. F.: C17H19NO5
• M. W.: 317.33646

SYNONYMS

• IUPAC name: 1-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-1,2,5,6-tetrahydropyridin-2-one
• IUPAC Traditional name: piperlongumine
• Synonyms: 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone; (E)-5,6-Dihydro-1-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)-pyridinone; Piplartine; 5,6-Dihydro-1-(3,4,5-trimethoxycinnamoyl)-2(1H)-pyridone; Piplartin

DATABASE IDS

• CAS Number: 20069-09-4

DETAILS

Description (English)

Piperlongumine (PL), a new alkaloid abundantly present in Piper longum fruits strongly inhibited platelet cell aggregation. It may have anti-cancer properties. It selectively targets and kills cancer cells but leaving normal cells unharmed.

REFERENCES

• Beretz, A., et al.: Planta Med., 57, 68 (1991)
• Lee, S., et al.: J. Microbiol. Biotechnol., 12, 679 (1991)
• Lee, K., et al.: Pharmacol. Res., 53, 265 (1991)