Pioglitazone-d4 Thiazolidinedione Ring-opened N-β-D-Glucuronide

• Catalog No.: P471022
• M. F.: C25H30N2O10S
• M. W.: 550.5781

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6R)-6-({[(1-carboxy-2-{4-[2-(5-ethylpyridin-2-yl)(^2H₄)ethoxy]phenyl}ethyl)sulfanyl]carbonyl}amino)-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6R)-6-({[(1-carboxy-2-{4-[2-(5-ethylpyridin-2-yl)(^2H₄)ethoxy]phenyl}ethyl)sulfanyl]carbonyl}amino)-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 1-[[[[1-Carboxy-2-[4-[2-(5-ethyl-2-pyridinyl)ethoxy-d4]phenyl]ethyl]thio]carbonyl]amino]-1-deoxy-β-D-glucopyranuronic Acid

DETAILS

Description (English)

A labelled ring-opened metabolite of Pioglitazone (P471015) formed via N-glucuronidation of thiazolidinedione ring.

REFERENCES

• Uchiyama, M. et al.: Drug Metab. Disp., 38, 946 (2010)