(αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetate

• Catalog No.: P458505
• CAS Number: 179324-87-9
• M. F.: C17H29BF3NO4
• M. W.: 379.2226696
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0^2,^6]decan-4-yl]butan-1-amine; trifluoroacetic acid
• IUPAC Traditional name: (1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0^2,^6]decan-4-yl]butan-1-amine; trifluoroacetic acid
• Synonyms: (1R)-(S)-Pinanediol-1-ammoniumtrifluoroacetate-3-methylbutane-1-boronate; (αR,3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-α-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-Trifluoroacetate

DATABASE IDS

• CAS Number: 179324-87-9

PROPERTIES

• Apperance: White Solid
• Melting Point: 159-161°C
• Solubility: Dimethylformamide
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Bortezomib (B675700) intermediate. A boronic acid dipeptide derivative as proteasome inhibitors.

REFERENCES

• Kisselev, A., et al.: Chem. Biol., 8, 739 (2001)
• Kisselev, A., et al.: J. Biol. Chem., 278, 35869 (2001)
• Verdoes, M., et al.: Chem. Biol., 13, 1217 (2001)