Picosulfate Sodium

• Catalog No.: P437550
• CAS Number: 10040-45-6
• M. F.: C18H13NNa2O8S2
• M. W.: 481.40726
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: disodium 4-{pyridin-2-yl[4-(sulfonatooxy)phenyl]methyl}phenyl sulfate
• IUPAC Traditional name: disodium 4-{pyridin-2-yl[4-(sulfonatooxy)phenyl]methyl}phenyl sulfate
• Synonyms: Laxoberon; Guttalax; DA 1773; Disodium Bis[4-[(hydroxysulfonyl)oxy]phenyl](2-pyridyl)methane; 4,4'-(2-Pyridinylmethylene)bisphenol 1,1'-Bis(hydrogen sulfate) Sodium Salt; 4,4'-(2-Pyridylmethylene)diphenol Bis(hydrogen sulfate) Disodium Salt; Evacuol; Neopax; Rapilax; Sodium Picosulfate

DATABASE IDS

• CAS Number: 10040-45-6

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 283-286°C
• Solubility: DMSO
• Solubility: Water
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria. Cathartic.

REFERENCES

• Perego, et al.: Arzneim.-Forsch., 19, 1889 (1969)
• Evan, M., et al.: J. Br. Med., 299, 1101 (1969)
• Castillo-Garit, J., et al.: Bioorg. Med. Chem., 14, 2398 (1969)