Phyllanthine

• Catalog No.: P397800
• CAS Number: 20072-02-0
• M. F.: C14H17NO3
• M. W.: 247.28968

SYNONYMS

• IUPAC name: (1R,2R,4R,8S)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0^1,^1^1.0^2,^7]pentadeca-9,11-dien-13-one
• IUPAC Traditional name: (1R,2R,4R,8S)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0^1,^1^1.0^2,^7]pentadeca-9,11-dien-13-one
• Synonyms: (-)-Phyllanthine; 4-Methoxysecurinine; (4β)-4-Methoxysecurinan-11-one; (6S,10R,11aR,11bS)-9,10,11,11a-Tetrahydro-10-methoxy-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one; 4β-Methoxysecurinine

DATABASE IDS

• CAS Number: 20072-02-0

DETAILS

Description (English)

A new alkaloid from Phyllanthus niruri. These alkaloids have found a sporadic use clinically for such diseases as poliomyelitis, ALS (amyotrophic lateral sclerosis) and chronic aplastic anemia.

REFERENCES

• Horii, Z., et al.: Chem. Pharm. Bull., 20, 1768 (1972)
• Rognan, D., et al.: J. Med. Chem., 35, 1969 (1972)
• Weenen, H., et al.: Planta Med., 56, 371 (1972)