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Phosphoramidon Disodium Salt

Catalog No. P359000 Name Toronto Research Chemicals
CAS Number 119942-99-3 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
(2S)-2-[(2S)-2-{[hydroxy({[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy})phosphoryl]amino}-4-methylpentanamido]-3-(1H-indol-3-yl)propanoic acid
IUPAC Traditional name
phosphoramidon
Synonyms
NSC 694280
N-[[(6-Deoxy-α-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl- L-tryptophan Disodium Salt

DATABASE IDS

CAS Number 119942-99-3

PROPERTIES

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DETAILS

Description (English)
An endothelin-converting enzyme inhibitor, attenuates lipopolysaccharide-induced acute lung injury.

REFERENCES

  • Kasahara, Y., et al.: J. Clin. Invest., 106, 1311 (2000)
  • Fagan, K., et al.: Respir. Res., 2, 90 (2000)
  • Thomas, P., et al.: Immunol. Cell Biol., 79, 132 (2000)
  • Douthwaite, J., et al.: Biochem. Pharmacol., 66, 589 (2000)
  • Wahl, J., et al.: Exp. Biol. Med