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4-Phenyl-3-furoxancarbonitrile

Catalog No. P322500 Name Toronto Research Chemicals
CAS Number 125520-62-9 Website http://www.trc-canada.com
M. F. C9H5N3O2 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
3-cyano-4-phenyl-1,2,5-oxadiazol-2-ium-2-olate
IUPAC Traditional name
3-cyano-4-phenyl-1,2,5-oxadiazol-2-ium-2-olate
Synonyms
Phenyl-furazancarbonitrile 2-Oxide
Furoxan, RVC-589

DATABASE IDS

CAS Number 125520-62-9

PROPERTIES

Certificate of Analysis Download
Apperance Crystalline Solid
Melting Point 73-74°C
MSDS Link Download

DETAILS

Description (English)
Able to activate the soluble guanylate cyclase by releasing Nitric Oxide under the action of thiol cofactors. Also inhibits platelet aggregation.

REFERENCES

  • Medana, C., et al.: J. Med. Chem., 37, 4412 (1994)
  • Feridi, R., et al.: Br. J. Pharm., 114, 816 (1994)
  • Liu, S.X., et al.: J. Ocul. Pharm. Ther., 13, 105 (1997)