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(6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester_Molecular_structure_CAS_265989-34-2)
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(6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

Catalog No. P319587 Name Toronto Research Chemicals
CAS Number 265989-34-2 Website http://www.trc-canada.com
M. F. C40H47FN2O5 Telephone +1 (416) 665-9696
M. W. 654.8099832 Fax +1 (416) 665-4439
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Storage Chembase ID: 176529

SYNONYMS

IUPAC name
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-(2H5)phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
IUPAC Traditional name
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-(2H5)phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Synonyms
(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenyl-d5-amino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester

DATABASE IDS

CAS Number 265989-34-2

PROPERTIES

Certificate of Analysis Download
Apperance Light-Yellow Foamy Solid
Solubility Acetone
Solubility Chloroform
Solubility Dichloromethane
Solubility Ethyl Acetate
MSDS Link Download

DETAILS

Description (English)
An deuterated intermediate of deuterated Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolem

REFERENCES

  • Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993)
  • Heinonen, T.M., et al.: Clin. Ther., 18. 853 (1993)
  • Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)