p-Phenetidine-d5 Hydrochloride

• Catalog No.: P296302
• M. F.: C8H12ClNO
• M. W.: 173.63998
• Storage: Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-(^2H₅)ethoxyaniline hydrochloride
• IUPAC Traditional name: 4-(^2H₅)ethoxyaniline hydrochloride
• Synonyms: p-Aminophenetole-d5 Hydrochloride; 4-Ethoxyaniline-d5 Hydrochloride; NSC 3116-d5 Hydrochloride; 4-(Ethoxy-d5)benzenamine Hydrochloride; p-Ethoxyaniline-d5 Hydrochloride; 1-Amino-4-(ethoxy-d5)benzene Hydrochloride; 4-Aminophenetole-d5 Hydrochloride; 4-(Ethoxy-d5)phenylamine Hydrochloride; p-(Ethoxy-d5)phenylamine Hydrochloride; p-Phenetidin-d5 Hydrochloride

PROPERTIES

• Apperance: Light Purple Solid
• Melting Point: 227-231°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Labelled p-Phenetidine (P296300). A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.

REFERENCES

• Green, C., et al.: Br. Med. J., 1, 162 (1969)
• Nelson, S., et al.: J. Med. Chem., 25, 753 (1969)
• Nicholls, A., et al.: Xenobiotica, 27, 1175 (1969)