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6-Phenanthridone

Catalog No. P294900 Name Toronto Research Chemicals
CAS Number 1015-89-0 Website http://www.trc-canada.com
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Storage Chembase ID: 68417

SYNONYMS

IUPAC name
5,6-dihydrophenanthridin-6-one
IUPAC Traditional name
5H-phenanthridin-6-one
Synonyms
NSC 40943
6(5H)-Phenanthridinone
5H-Phenanthridin-6-one
PJ 97A
6-Phenanthridinol
6-Phenanthridinone
6-Phenanthridone
WD 99-004344
NSC 11021
NSC 61083

DATABASE IDS

CAS Number 1015-89-0

PROPERTIES

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DETAILS

Description (English)
6-Phenanthridone is a poly(ADP-ribose) polymerase (PARP) inhibitor with immunosuppressive effects. 6-Phenanthridone has been shown to inhibit concanavalin A-induced lymphocyte proliferation.

REFERENCES

  • Chiarugi, A. et al.: Br. J. Pharmacol., 137, 761 (2002)
  • Nasrabady, S.E. et al.: Cell. Mol. Neurobiol., 31, 503 (2002)
  • Weltin, D. et al.: Int. J. Immunopharmacol., 17, 265 (2002)