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PF-998425_Molecular_structure_CAS_1076225-27-8)
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PF-998425

Catalog No. P294060 Name Toronto Research Chemicals
CAS Number 1076225-27-8 Website http://www.trc-canada.com
M. F. C14H14F3NO Telephone +1 (416) 665-9696
M. W. 269.2622696 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 176425

SYNONYMS

IUPAC name
(1R,2R)-2-[4-isocyano-3-(trifluoromethyl)phenyl]cyclohexan-1-ol
IUPAC Traditional name
(1R,2R)-2-[4-isocyano-3-(trifluoromethyl)phenyl]cyclohexan-1-ol
Synonyms
rel-(-)-4-[(1R,2R)-2-Hydroxycyclohexyl]-2-(trifluoromethyl)benzonitrile

DATABASE IDS

CAS Number 1076225-27-8

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
PF-998425 is a novel, nonsteroidal androgen receptor antagonist for sebum control and treatment of androgenetic alopecia.

REFERENCES

  • Koch, H., et al.: Drugs Today, 20, 561 (1984)
  • Bernard, E., et al.: J. Pharm. Sci., 86, 573 (1984)
  • Singh, S., et al.: Curr. Med. Chem., 2000, 7, 211 (1984)
  • Hu, L., et al.: Bioorg. Med. Chem. Lett., 2007, 17, 5693 (1984)