PF-03716556

• Catalog No.: P293980
• CAS Number: 928774-43-0
• M. F.: C22H26N4O3
• M. W.: 394.46684
• Storage: Refrigerator

SYNONYMS

• IUPAC name: N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-1-benzopyran-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide
• IUPAC Traditional name: N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-1-benzopyran-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide
• Synonyms: PF 3716556; 8-[[(4R)-3,4-Dihydro-5-methyl-2H-1-benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dimethylimidazo[1,2-a]pyridine-6-carboxamide; N-(2-Hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide

DATABASE IDS

• CAS Number: 928774-43-0

PROPERTIES

• Apperance: Light Tan Solid
• Melting Point: 143-145°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease.

REFERENCES

• Sachs, G., et al.: J. Biol. Chem., 251, 7690 (1976)
• Wallmark, B., et al.: J. Biol. Chem., 262, 2077 (1976)
• Keeling, D., et al.: Biochem. Pharmacol., 37, 2231 (1976)
• Robinson, M., et al.: Drugs, 63, 2739 (1976)