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PF-514273_Molecular_structure_CAS_851728-60-4)
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PF-514273

Catalog No. P293900 Name Toronto Research Chemicals
CAS Number 851728-60-4 Website http://www.trc-canada.com
M. F. C21H17Cl2F2N3O2 Telephone +1 (416) 665-9696
M. W. 452.2813864 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 128904

SYNONYMS

IUPAC name
2-(2-chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-2H,5H,6H,7H,8H-pyrazolo[3,4-f][1,4]oxazepin-8-one
IUPAC Traditional name
2-(2-chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-5H,6H-pyrazolo[3,4-f][1,4]oxazepin-8-one
Synonyms
2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-f][1,4]oxazepin-8(5H)-one
PF 514273

DATABASE IDS

CAS Number 851728-60-4

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 158-160°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A novel, bicyclic lactam-based cannabinoid-1 receptor antagonist for the treatment of obesity.

REFERENCES

  • Hao, S., et al.: Eur. J. Pharmacol., 392, 147 (2000)
  • Kershaw, E., et al.: J. Clin. Endocrinol. Metab., 89, 2548 (2000)
  • Engeli, S., et al.: Diabetes, 54, 2838 (2000)
  • Lin, L., et al.: J. Med. Chem., 49, 7584 (2000)