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PF 3845_Molecular_structure_CAS_1196109-52-0)
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PF 3845

Catalog No. P293760 Name Toronto Research Chemicals
CAS Number 1196109-52-0 Website http://www.trc-canada.com
M. F. C24H23F3N4O2 Telephone +1 (416) 665-9696
M. W. 456.4602296 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 73163

SYNONYMS

IUPAC name
N-(pyridin-3-yl)-4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methyl]piperidine-1-carboxamide
IUPAC Traditional name
N-(pyridin-3-yl)-4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methyl]piperidine-1-carboxamide
Synonyms
N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide

DATABASE IDS

CAS Number 1196109-52-0

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
PF 3845 is a selective fatty acid amide hydrolase (FAAH) inhibitor (Ki = 0.23 μM). Reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. Highly efficacious and selective in vivo. Displays no activity at FAAH-2 (IC50 >10 μM).

REFERENCES

  • Ahn, et al.: Chem. Biol., 16, 411 (2009)
  • Ahn, et al.: Expert. Opin. Drug Discov., 4 763 (2009)