Pentoxifylline-d6

• Catalog No.: P276502
• CAS Number: 1185878-98-1
• M. F.: C13H18N4O3
• M. W.: 278.30702
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 3,7-bis(^2H₃)methyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• IUPAC Traditional name: 3,7-bis(^2H₃)methyl-1-(5-oxohexyl)purine-2,6-dione
• Synonyms: Oxpentifylline-d6; Vazofirin-d6; 1-(5-Oxohexyl)theobromine-d6; 1-(5-Oxohexyl)-3,7-(dimethyl-d6)xanthine-d6; 3,7-Dihydro-3,7-(dimethyl-d6)-1-(5-oxohexyl)-1H-purine-2,6-dione; Trental-d6

DATABASE IDS

• CAS Number: 1185878-98-1

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 81-83°C
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A labelled metabolite of Pentifylline. Methylxanthine derivative that improves blood flow by decreasing blood viscosity. Phosphodiesterase inhibitor. Inhibits the synthesis of tumor necrosis factor α (TNF-α).

REFERENCES

• Ward, A., et al.: Drugs, 34, 50 (1987)
• Samlaska, C.P., et al.: J. Am. Acad. Dermatol., 30, 603 (1987)
• Poulakis, et al.: Respir. Med., 93, 52 (1987)
• Reuter, et al.: Am J. Physiol., 277, 854 (1987)