Pentamidine Isethionate

• Catalog No.: P272501
• M. F.: C21H30N4O6S
• M. W.: 466.5511

SYNONYMS

• IUPAC name: 2-hydroxyethane-1-sulfonic acid; 4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide
• IUPAC Traditional name: pentamidine sodium isethionate
• Synonyms: Pentacarinat; 4,4'-(Pentamethylenedioxy)di-benzamidine Diisethionate; 4,4'-Diamidinodiphenoxypentane di(β-hydroxyethanesulfonate); Pentam 300; Banambax; NebuPent; 4,4'-[1,5-Pentanediylbis(oxy)]bis-benzenecarboximidamide Bis(2-hydroxyethanesulfonate); 1,5-Bis(4-amidinophenoxy)pentane Diisethionate; Aeropent; Diamidine; Lomidin; Lomidine; M & B 800; Pentam

DETAILS

Description (English)

Has been widely used as a drug to treat protozoal diseases, such as malaria, amoebic dysentery and trypanosomiasis. It has also been shown to be effective for both prophylaxis of pneumocystic carinii pneumonia (PCC).

REFERENCES

• Goa, K.L., et al.: Drugs, 33, 242 (1987)
• Debs, R.J., et al.: Antimicrob. Agents Chemother., 31, 37 (1987)
• Walzer, P.D., et al.: Antimicrob. Agents Chemother., 32, 896 (1987)
• Hesk, D., et al.: J. Lab. Comp. Radiopharm., 28, 11, 1309 (1990)