Pentamidine

• Catalog No.: P272500
• CAS Number: 100-33-4
• M. F.: C19H24N4O2
• M. W.: 340.41946
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide
• IUPAC Traditional name: pentamidine
• Synonyms: 4,4'-Diamidino-.alpha.,.omega.-diphenoxypentane; MP 601205; 4,4'-[1,5-Pentanediylbis(oxy)]bis-benzenecarboximidamide; NSC 9921; p,p'-(Pentamethylenedioxy)dibenzamidine

DATABASE IDS

• CAS Number: 100-33-4

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 198-200°C (dec.)
• Solubility: DMSO
• Solubility: Methanol (Sparingly)
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Has been widely used as a drug to treat protozoal diseases, such as malaria, amoebic dysentery and trypanosomiasis. It has also been shown to be effective for both prophylaxis of pneumocystic carinii pneumonia (PCC).

REFERENCES

• Goa, K.L., et al.: Drugs, 33, 242 (1987)
• Debs, R.J., et al.: Antimicrob. Agents Chemother., 31, 37 (1987)
• Walzer, P.D., et al.: Antimicrob. Agents Chemother., 32, 896 (1987)
• Hesk, D., et al.: J. Lab. Comp. Radiopharm., 28, 11, 1309 (1990)