PD-173952

• Catalog No.: P217800
• CAS Number: 305820-75-1
• M. F.: C24H21Cl2N5O2
• M. W.: 482.36184

SYNONYMS

• IUPAC name: 6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4-yl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
• IUPAC Traditional name: 6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7-one
• Synonyms: 6-(2,6-Dichlorophenyl)-8-methyl-2-[[4-(4-morpholinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one

DATABASE IDS

• CAS Number: 305820-75-1

DETAILS

Description (English)

A Bcr-Abl tyrosine kinase inhibitor used in treatment research for chronic myelegenous leukemia (CML).

REFERENCES

• Dorsey, J.F. et al.: Leukemia, 16, 1589 (2002)
• Wisniewski, D. et al.: Canc. Res., 62, 4244 (2002)
• Mizenina, O.A. et al.: Cell Cycle, 3, 796 (2002)