PD 144418 Oxalate

• Catalog No.: P217520
• CAS Number: 154130-99-1
• M. F.: C20H24N2O5
• M. W.: 372.41496

SYNONYMS

• IUPAC name: 5-[3-(4-methylphenyl)-1,2-oxazol-5-yl]-1-propyl-1,2,3,6-tetrahydropyridine; oxalic acid
• IUPAC Traditional name: 3-[3-(4-methylphenyl)-1,2-oxazol-5-yl]-1-propyl-5,6-dihydro-2H-pyridine; oxalic acid
• Synonyms: 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine Oxalate

DATABASE IDS

• CAS Number: 154130-99-1

DETAILS

Description (English)

PD 144418 is high affinity, selective σ1 ligand (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively). PD 144418 displays no significant activity at a wide range of other receptors, ion channels and enzymes. PD 144418 antagonizes mescaline-induced s

REFERENCES

• Walker, J., et al.: Pharmacol. Rev., 42, 355 (1990)
• Akunne, et al.: Neuropharmacology, 36, 51 (1990)
• Jbilo, O., et al.: J. Biol. Chem., 272, 27107 (1990)