D-(-)-Pantolactone-d6

• Catalog No.: P182502
• M. F.: C6H10O3
• M. W.: 130.1418

SYNONYMS

• IUPAC name: (3R)-3-hydroxy-4,4-bis(^2H₃)methyloxolan-2-one
• IUPAC Traditional name: (3R)-3-hydroxy-4,4-bis(^2H₃)methyloxolan-2-one
• Synonyms: D-(-)-α-Hydroxy-β,β-(dimethyl-d6)-γ-butyrolactone; (3R)-Tetrahydro-3-hydroxy-4,4-(dimethyl-d6)furan-2-one; (-)-2-Hydroxy-3,3-(dimethyl-d6)-γ-butyrolactone; Pantothenic Lactone-d6; (3R)-Dihydro-3-hydroxy-4,4-(dimethyl-d6)-2(3H)-furanone; (-)-(R)-Pantolactone-d6; (-)-Pantoyl Lactone-d6; (R)-α-Hydroxy-β,β-(dimethyl-d6)-γ-butyrolactone

DETAILS

Description (English)

A labelled intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.

REFERENCES

• Williams, M.: Science, 91, 246 (1940)
• Glaser et al.: Monatsch. Chem., 25, 46 (1940)
• Stiller et al.: J. Am. Chem. Soc., 62, 1785 (1940)
• Dorofeev, B.F. et al.: Dep. Doc., 14 (1940)