D-(-)-Pantolactone

• Catalog No.: P182500
• CAS Number: 599-04-2
• M. F.: C6H10O3
• M. W.: 130.1418

SYNONYMS

• IUPAC name: (3R)-3-hydroxy-4,4-dimethyloxolan-2-one
• IUPAC Traditional name: pantolactone
• Synonyms: (-)-2-Hydroxy-3,3-dimethyl-γ-butyrolactone; D-(-)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone; Pantothenic Lactone; (3R)-Tetrahydro-3-hydroxy-4,4-dimethylfuran-2-one; (-)-(R)-Pantolactone; (3R)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone; (-)-Pantoyl Lactone; (R)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone

DATABASE IDS

• CAS Number: 599-04-2

DETAILS

Description (English)

An important intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.

REFERENCES

• Williams, M.: Science, 91, 246 (1940)
• Glaser et al.: Monatsch. Chem., 25, 46 (1940)
• Stiller et al.: J. Am. Chem. Soc., 62, 1785 (1940)
• Dorofeev, B.F. et al.: Dep. Doc., 14 (1940)