Toronto Research Chemicals ID P141002

• Catalog No.: P141002
• CAS Number: 1020719-55-4
• M. F.: C23H27FN4O3
• M. W.: 426.4838832
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl](^2H₄)ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one
• IUPAC Traditional name: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl](^2H₄)ethyl}-9-hydroxy-2-methyl-6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one
• Synonyms: R 76477-d4; 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-d4]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; RO 76477-d4; 9-Hydroxyrisperidone-d4; Risperidone Imp. C (EP)-d4

DATABASE IDS

• CAS Number: 1020719-55-4

PROPERTIES

• Apperance: Off White to Light Orange Coloured Solid
• Melting Point: 158-160°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A deuterated analog of Paliperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.

REFERENCES

• Kerr, K., et al.: J. Biol. Chem., 276, 8657 (1996)
• Doran, A., et al.: Drug Metab. Dispos., 33,
• Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (1996)
• Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996)
• Kansy, M., et al.: J. Med. Chem., 41, 1007 (1996)