Paclitaxel Oxetane Ring-Opened 3-Acetyl 4-Benzoyl Impurity

• Catalog No.: P132520
• CAS Number: 932042-85-8
• M. F.: C47H53NO15
• M. W.: 871.92142

SYNONYMS

• IUPAC name: [(1S,2S,3R,4S,5S,7S,8S,10R,13S)-5,10-bis(acetyloxy)-1,2,4,7-tetrahydroxy-13-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.0^3,^8]pentadec-11-en-4-yl]methyl benzoate
• IUPAC Traditional name: [(1S,2S,3R,4S,5S,7S,8S,10R,13S)-5,10-bis(acetyloxy)-1,2,4,7-tetrahydroxy-13-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.0^3,^8]pentadec-11-en-4-yl]methyl benzoate
• Synonyms: β-(Benzoylamino)-α-hydroxybenzenepropanoic Acid (αR,βS)-(1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Bis(acetyloxy)-4-[(benzoyloxy)methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetramethyl-12-oxo-6,10-methanobenzocyclodecen-8-yl Ester

DATABASE IDS

• CAS Number: 932042-85-8

DETAILS

Description (English)

An oxetane ring-opened impurity of Paclitaxel (P132500) with no significant activity.

REFERENCES

• Pyo, S.-H. et al.: J. Pharmac. Biomed. Anal., 43, 1141 (2007)