Paclitaxel C

• Catalog No.: P132510
• CAS Number: 153415-45-3
• M. F.: C46H57NO14
• M. W.: 847.94308

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-hexanamido-2-hydroxy-3-phenylpropanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-hexanamido-2-hydroxy-3-phenylpropanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: Taxuyunnanine A; Taxuyunnanine; Taxol C; (-)-Taxuyunnanine; N-Debenzoyl-N-hexanoylpaclitaxel

DATABASE IDS

• CAS Number: 153415-45-3

DETAILS

Description (English)

Paclitaxel related compound C. Paclitaxel analogs were tested for tubulin assembly and cytotoxicity, and were shown to retain potency similar to Paclitaxel.

REFERENCES

• Ojima, I., et al.: J. Med. Chem., 38, 3891 (1995)
• van Asperen, J., et al.: J. Pharm. Sci., 86, 881 (1995)
• Fellner, S., et al.: J. Clin. Invest., 110, 1309 (1995)
• Beckers, T., et al.: Drugs Future, 28, 767 (1995)
• Kemper, E., et al.: Clin. Cancer Res.,