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Paclitaxel

Catalog No. P132500 Name Toronto Research Chemicals
CAS Number 33069-62-4 Website http://www.trc-canada.com
M. F. C47H51NO14 Telephone +1 (416) 665-9696
M. W. 853.90614 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 1098

SYNONYMS

IUPAC name
(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
IUPAC Traditional name
taxol
Synonyms
Pacliex
NSC 125973
Genaxol
Taxol
Abraxane
Genetaxyl
OncoGel
Onxal
(-)-Paclitaxel
Yewtaxan

DATABASE IDS

CAS Number 33069-62-4

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 214-216°C
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic i

REFERENCES

  • Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984)
  • Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984)
  • Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1984)
  • Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (1984)
  • Stone, G.W., et al.: