4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

• Catalog No.: O864950
• CAS Number: 764667-65-4
• M. F.: C16H12F6N4O2
• M. W.: 406.2824992
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
• IUPAC Traditional name: 1-[3-(trifluoromethyl)-5H,6H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
• Synonyms: rac-Sitagliptin 3-Ketone; 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1,3-butanedione

DATABASE IDS

• CAS Number: 764667-65-4

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 82-84°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Sitagliptin intermediate.

REFERENCES

• Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982)
• Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (1982)