10-Oxo Naltrexone Methyl Ether

• Catalog No.: O858210
• CAS Number: 96445-13-5
• M. F.: C21H23NO5
• M. W.: 369.41102
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (1S,5S,13R,17S)-4-(cyclopropylmethyl)-17-hydroxy-10-methoxy-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-6,14-dione
• IUPAC Traditional name: (1S,5S,13R,17S)-4-(cyclopropylmethyl)-17-hydroxy-10-methoxy-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-6,14-dione
• Synonyms: (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-14-hydroxy-3-methoxy-morphinan-6,10-dione; 10-Ketonaltrexone-3-methyl Ether; 10-Oxo-3-O-methylnaltrexone

DATABASE IDS

• CAS Number: 96445-13-5

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 90-95°C
• Solubility: Dichloromethane
• Solubility: DMSO
• Storage Condition: Refrigerator

DETAILS

Description (English)

Naltrexone derivative, showing significantly less potency than pure Naltrexone.

REFERENCES

• Archer, S., et al.: J. Med. Chem., 28, 974 (1985)