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10-Oxo Docetaxel_Molecular_structure_CAS_167074-97-7)
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10-Oxo Docetaxel

Catalog No. O855800 Name Toronto Research Chemicals
CAS Number 167074-97-7 Website http://www.trc-canada.com
M. F. C43H51NO14 Telephone +1 (416) 665-9696
M. W. 805.86334 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 176008

SYNONYMS

IUPAC name
(1S,2S,3R,4S,7R,9S,10S,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11,12-dioxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
IUPAC Traditional name
(1S,2S,3R,4S,7R,9S,10S,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11,12-dioxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
Synonyms
(αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic Acid (2aR,4S,4aS,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester

DATABASE IDS

CAS Number 167074-97-7

PROPERTIES

Certificate of Analysis Download
Apperance Pale Yellow Solid
Melting Point 135-143°C (dec.)
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
A novel taxoid having remarkable anti-tumor properties. Docetaxel (D494420) intermediate.

REFERENCES

  • Appendino, G., et al.: Tetrahedron Lett., 37, 7836 (1996)