8-Oxo-2'-deoxyguanosine-13C,15N2

• Catalog No.: O850252
• M. F.: C10H13N5O5
• M. W.: 286.22019263
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-amino-8-hydroxy-9-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro(2-^1^3C,1-^1^5N)-1H-purin-6-one
• IUPAC Traditional name: 2-amino-8-hydroxy-9-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](2-^1^3C,1-^1^5N)-1H-purin-6-one
• Synonyms: 8-Oxo-dG-13C,15N2; 8-Oxo-7,8-dihydro-2'-deoxyguanosine-13C,15N2; 8-Oxo-7,8-dihydrodeoxyguanosine-13C,15N2; 8-Hydroxy-2’-deoxyguanosine-13C,15N2; 2'-Deoxy-7,8-dihydro-8-oxo-guanosine-13C,15N2

PROPERTIES

• Apperance: White Solid
• Melting Point: 195-200°C
• Solubility: DMSO
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.

REFERENCES

• Ueda, T., et al.: Chem. Pharm. Bull., 26, 2122 (1978)
• Jiang, F., et al.: Nature, 183, 382 (1978)