8-Oxo-2'-deoxyguanosine

• Catalog No.: O850250
• CAS Number: 88847-89-6
• M. F.: C10H13N5O5
• M. W.: 283.24072
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-amino-8-hydroxy-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
• IUPAC Traditional name: 2-amino-8-hydroxy-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
• Synonyms: 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 8-Hydroxy-2’-deoxyguanosine; 8-Oxo-dG; 2'-Deoxy-7,8-dihydro-8-oxo-guanosine

DATABASE IDS

• CAS Number: 88847-89-6

PROPERTIES

• Solubility: DMSO
• Solubility: Methanol
• Apperance: White to Off-White Solid
• Melting Point: 205-210°C (dec.)
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.

REFERENCES

• Ueda, T., et al.: Chem. Pharm. Bull., 26, 2122 (1978)
• Jiang, F., et al.: Nature, 183, 382 (1978)