3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester

• Catalog No.: O847260
• CAS Number: 103335-41-7
• M. F.: C20H29NO3
• M. W.: 331.44916
• Storage: Refrigerator

SYNONYMS

• IUPAC name: methyl (2R,7R,10S,11S,14R,15S)-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-3-ene-14-carboxylate
• IUPAC Traditional name: methyl (2R,7R,10S,11S,14R,15S)-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-3-ene-14-carboxylate
• Synonyms: (5α,17β)-3-Oxo-4-azaandrost-1-ene-17-carboxylic Acid Methyl Ester; Finasteride Impurity; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid Methyl Ester; Methyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate

DATABASE IDS

• CAS Number: 103335-41-7

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 280-282°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Finasteride (F342000) impurity. A novel intermediate in the synthesis of Finasteride, a 5α-reductase inhibitor used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrog

REFERENCES

• Bakshi., et al.: J. Med. Chem., 38, 3189 (1995)