(S,S)-Oxaliplatin_Molecular_structure_CAS_61758-77-8)

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(S,S)-Oxaliplatin
Catalog No.	O845080	Name	Toronto Research Chemicals
CAS Number	61758-77-8	Website	http://www.trc-canada.com
M. F.	C8H12N2O4Pt	Telephone	+1 (416) 665-9696
M. W.	395.26988	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 175961

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SYNONYMS

IUPAC name

platinum(4+) ion (1S,2S)-cyclohexane-1,2-diaminide oxalate

IUPAC Traditional name

platinum(4+) ion (1S,2S)-cyclohexane-1,2-diaminide oxalate

Synonyms

(SP-4-2)-[(1S,2S)-1,2-Cyclohexanediamine-kN,kN'][ethanedioato(2-)-kO1,kO2]platinum

[SP-4-2-(1S-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']platinum

(1S-trans)-1,2-Cyclohexanediamine Platinum Complex

DATABASE IDS

CAS Number

61758-77-8

PROPERTIES

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DETAILS

Description (English)

The (S,S) Oxaliplatin isomer. Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.

REFERENCES

Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978)
Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1978)
Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1978)
Simpson, D., et al.: Drugs, 63, 2127 (1978)