Oxaliplatin

• Catalog No.: O845075
• CAS Number: 61825-94-3
• M. F.: C8H12N2O4Pt
• M. W.: 395.26988
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: platinum(4+) ion (1R,2R)-cyclohexane-1,2-diaminide oxalate
• IUPAC Traditional name: platinum(4+) ion (1R,2R)-cyclohexane-1,2-diaminide oxalate
• Synonyms: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']platinum; Dacplat; Elplat; Lipoxal; (1R-trans)-1,2-Cyclohexanediamine Platinum Complex; (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN'][ethanedioato(2-)-kO1,kO2]platinum; Eloxatin; Oxalatoplatinum

DATABASE IDS

• CAS Number: 61825-94-3

PROPERTIES

• Apperance: White Solid
• Melting Point: >245°C (dec.)
• Solubility: DMSO
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.

REFERENCES

• Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978)
• Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1978)
• Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1978)
• Simpson, D., et al.: Drugs, 63, 2127 (1978)