Oripavine

• Catalog No.: O675000
• CAS Number: 467-04-9
• M. F.: C18H19NO3
• M. W.: 297.34836
• Storage: Controlled Substance, -20°C Freezer

SYNONYMS

• IUPAC name: (1S,5S,13R)-14-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10,14,16-pentaen-10-ol
• IUPAC Traditional name: (1S,5S,13R)-14-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10,14,16-pentaen-10-ol
• Synonyms: (5α)-6,7,8,14-Tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol; 3-O-Demethylthebaine

DATABASE IDS

• CAS Number: 467-04-9

PROPERTIES

• Apperance: Light Tan Solid
• Melting Point: >155°C (dec.)
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Controlled Substance, -20°C Freezer

DETAILS

Description (English)

The major metabolite of Thebaine. Oripavine possesses an analgesic potency comparable to Morphine; it is not clinically useful due to severe toxicity and low therapeutic index. An opiate.

REFERENCES

• Barber, R., et al.: J. Med. Chem., 18, 1074 (1975)
• Yamazoe, Y., et al.: J. Pharmacol., 31, 433 (1975)